Erlotinib intermediates manufacturer
CAS No.:850649-62-6
Other Names:Alogliptin Benzoate
MF:C18H21N5O2
Type:
Antibiotic and Antimicrobial Agents, Auxiliaries and Other Medicinal Chemicals
Grade Standard:
Medicine Grade, Tech Grade
Purity:99%min
Appearance:White powder
Specification:99.0% (HPLC)
Storage:Cool and dry
Package:foil bag
Technical support::Available
SupplyAbility
3000 Kilogram/Kilograms per Month
Packaging & Delivery
Packaging Details
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
Port:Any port in China
Lead Time : Shipped in 3 days after payment
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Product Name: |
ALOGLIPTIN BENZOATE |
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Synonyms: |
ALOGLIPTIN BENZOATE;2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile benzoate;2-[[6-[(3R)-3-aMino-1-piperidinyl]-3,4-dihydro-3-Methyl-2,4-dioxo-1(2H)-pyriMidinyl]Methyl]-Benzonitrile Monobenzoate;SYR 322;Nesina;2-[6-[3(R)-AMinopiperidin-1-yl]-3-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyriMidin-1-ylMethyl]benzonitrile benzoate;(R)-2-((6-(3-aMinopiperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)benzonitrile benzoate;2-[6-[3(R)-AMinopiperidin-1-yl]-3-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyriMidin-1-ylMethyl]benzonitrile benzoate Monobenzoate |
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CAS: |
850649-62-6 |
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MF: |
C18H21N5O2.C7H6O2 |
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MW: |
461.519 |
Alogliptin is an orally administered anti-diabetic drug in the DPP-4 inhibitor class,developed , a company which was acquired by Takeda Pharmaceutical Company in 2005. Like other medications for the treatment of Type 2 diabetes, alogliptin does not decrease the risk of heart attack and stroke. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.
Specification:
|
Item |
Specifications |
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Appearance |
White or white crystalline powder |
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Identification |
IR conform to Ref standard |
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Heavy metals |
10ppm max |
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Loss on drying |
0.50% max |
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Melting point |
126-131°C |
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Total impurities |
0.3% max |
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Related compound A |
0.10% max |
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Any unspecified impurity |
0.10% max |
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Enantiomers |
Not detected |
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Residue on ignition |
0.1% max |
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Assay (on the dried basis) |
98.0% to 102.0% |
Application:
suitable for the treatment of type 2 diabetes
