Capecitabine

Introduction 

Other name: Pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate

CAS NO.:154361-50-9

MF:C15H22FN3O6

MW: 359.35

InChI: 1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)

Melting point: 110~121℃

Appearance:white or off-white crystalline powder

Specification:99%min

Standard: EP/BP/USP

Odor: odorless

Function:

Classification: Antineoplastic, antimetabolite Action/Kinetics: An oral prodrug of 5'-deoxy-5-fluorouridine (5'DFUR) that is converted to 5-fluorouracil (5-FU). 5-FU is metabolized to 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) which cause cell injury in two ways. First, FdUMP and the folate cofactor, N5-10-methylenetetrahydrofolate, bind to thymidylate synthase to form a covalently bound ternary complex which inhibits the formation of thymidylate from uracil. Thymidylate is essential for the synthesis of DNA so a deficiency inhibits cell division. Secondly, nuclear transcriptional enzymes can mistakenly incorporate FUTP in place of uridine triphosphate during RNA synthesis; this interferes with RNA processing and protein synthesis. Readily absorbed from the GI tract. Peak blood levels, capecitabine: 1.5 hr; peak blood levels, 5-FU: 2 hr. Food reduces the rate and extent of absorption. t1/2, capecitabine and 5-FU: 45 min. Metabolites excreted in the urine.

Application  

 1. Natural d alpha tocopherol, Tocopherol Powder Applied in the Cosmetics industry, mixed tocopherol can prevent the premature aging of skin and improve the skin's elasticity.
2. Natural d alpha tocopherol, Tocopherol Powder Applied in the Medical industry, mixed tocopherol can be used in curing pericoronitis, fatty liver, and arteriosclerosis, habitual abortion and barrenness.
3. Natural d alpha tocopherol, Tocopherol Powder Applied in the Food industry, mixed tocopherol is mainly used as an antioxidant and a fortifying agent of fatty foods,and nutritional reinforcing agent of health care product.
4. Natural d alpha tocopherol, Tocopherol Powder Applied in feed additive for livestock, mixed tocopherol is mainly used as an antioxidant it can improve the reproductive functions of animals and increase reproductive capacity.

Specification  

SupplyAbility

4000 Kilogram/Kilograms per Month

Packaging & Delivery

25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside. 
Delivery Detail: within 3 days when get the payment

Port

Any port in china

Lead Time :3 days when get the payment