Afatinib Dimaleate is the dimaleate salt way of afatinib, an orally bioavailable anilino-quinazoline derivative and inhibitor with the receptor tyrosine kinase (RTK) epidermal growth receptor (ErbB; EGFR) family, with antineoplastic activity. Upon administration, afatinib selectively and irreversibly binds to and inhibits the epidermal growth receptors 1 (ErbB1; EGFR), 2 (ErbB2; HER2), and 4 (ErbB4; HER4), and certain EGFR mutants, including those brought on by EGFR exon 19 deletion mutations or exon 21 (L858R) mutations.
Afatinib Dimaleate is very important that you take tablets according to the instructions your doctor or pharmacist gave you. Whether you have a full or empty stomach can affect how much of a drug gets into your bloodstream. You should take the right dose, not more or less. And never stop taking a cancer drug without talking to your specialist first.
If you accidentally take too much afatinib, see a doctor or go to a hospital straight away. If you forget to take a dose of afatinib and your next dose is due after more than 8 hours, take the missed dose as soon as you remember. If the next dose is due in less than 8 hours, skip the missed dose and take the next dose at the usual time. Don't take a double dose to make up for the missed one.
You usually continue taking afatinib for as long as it works, unless it causes bad side effects.
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