Shijiazhuang Dingmin Pharmaceutical Sciences Co., Limited supply low price
Axitinb 319460-85-0.
Cas No.: 319460-85-0
Product Name: Axitinib
Appearance:Off-white solid
Molecular Weight:386.47
Density:1.35 g/cm3
Boiling Point:668.9 oC at 760 mmHg
Melting Point:213-215 oC
Flash Point:358.3 oC
Refractive index:1.728
Usage:A tyrosine kinase inhibitor; used in cancer therapy.
Apperance: White powder
Specification: 99%
Axitinib (AG013736; trade name Inlyta) inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT(CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft models and has been successful in trials with renal cell carcinoma (RCC) and several other tumor types.
Diarrhea, hypertension, fatigue, decreased appetite, nausea, dysphonia, hand-foot syndrome, weight decreased, vomiting, asthenia, and constipation are the most common side effects occurring in more than 20% of patients
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